ABSTRACT
Bronchial asthma is one of the most common chronic inflammatory disorders in children.Pharmacotherapy can effectively control the chronic airway inflammation,improve the lung function,but it is difficult to improve the underlying immune response and natural progression of allergic diseases.Allergen specific immunotherapy can modify the course of allergic disease,reducing the risk of new allergic sensitizations,deterring the development of clinical asthma in children treated for allergic rhinitis and induce specific immune tolerance.The principal types of AIT are subcutaneous allergen immunotherapy (SCIT) and sublingual allergen immunotherapy (SLIT).Dust mite is a common type of allergen.Dust mite SLIT has been widely used in clinic due to its effectiveness and safety.